1025967-78-5 liftEmast

Egenskaper

Utseende hvitt til off-white faststoff
Melting point:>163 grad (des.)
Kokepunkt: 811,9 ± 65. 0 grad
Tetthet 1.479 ± 0. 06 g/cm3
lagringstemp. Hygroskopisk, -20 grad Fryser, under inert atmosfære
Løselighet DMSO (litt, oppvarmet, sonikert), metanol (litt, sonikert)
PKA3.14 ± 0. 10

 

Søknad:

Lifitegrast reduserer aggregeringen av hvite blodlegemer i øyet ved å blokkere samspillet mellom LFA -1 og ICAM -1, og dermed lindre øyebetennelse og tørre øyesymptomer. Denne mekanismen gjør at Lifitegrast har potensiale i behandlingen av tørr øyesykdom.

 

Synonymer:

Lifitegrast

1025967-78-5

Xiidra

SAR -1118

(S) -2- (2- (benzofuran -6- karbonyl) -5, 7- dichloro -1, 2,3, 4- tetra hydroisoquinoline -6- carboxamido) -3- (3- (metylsulfonyl) fenyl) propanoisk syre

SHP -606

L-fenylalanin, N-[[2- (6- benzofuranylcarbonyl) -5, 7- dichloro -1, 2,3, { {9}} tetrahydro -6- isoquinolinyl] karbonyl] -3- (metylsulfonyl)-

SAR1118

L-fenylalanin, N-((2- (6- benzofuranylcarbonyl) -5, 7- dichloro -1, 2,3, { {9}} tetrahydro -6- isoquinolinyl) karbonyl) -3- (metylsulfonyl)-

(2s) -2- (((2- (benzofuran -6- ylcarbonyl) -5, 7- dichloro -1, 2,3, {{9} {teth ydroisoquinolin -6- yl) karbonyl) amino) -3- (3- (metylsulfonyl) fenyl) propanisk syre

(2s) -2- [[2- (1- Benzofuran -6- karbonyl) -5, 7- dichloro -3, {8}} {-3 7-}}} {-3 {{{5 {5 { -1 h-isoquinoline -6- karbonyl] amino] -3- (3- metylsulfonylfenyl) propanoisk syre

Lifitegrast

LIFITEGRASTUM

L-fenylalanin, N-[[2- (6- benzofuranylcarbonyl) -5, 7- dichloro -1, 2,3, { {9}} tetrahydro -6- isoquinolinyl] karbonyl] -3- (metylsulfonyl)-; N-[[2- (6- benzofuranylcarbonyl) -5, 7- dichloro -1, 2,3, 4- t etrahydro -6- isoquinolinyl] karbonyl] -3- (metylsulfonyl) -l-fenylalanin; (S)

N-(2- (1- benzofuran -6- karbonyl) -5, 7- dichloro -1, 2,3, 4- TE Trahydroisoquinoline -6- karbonyl) -3- (Methanesulfonyl) -l-fenylalanin

(S) -2- (2- (benzofuran -6- karbonyl) -5, 7- dichloro -1, 2,3, 4- tetra hydroisoquinoline -6- carboxamido) -3- (3- (metylsulfonyl) fenyl) propanoisk syre; (s) -2- (2- (benzofuran -6- karbonyl) {15}}, 7- dichloro -1, 2,3, 4- tetrahydroisoquinoline -6- carboxamido) -3- ({3- (metylsulfonyl) fenyl) propanoisk syre

) yl) karbonyl) amino) -3- (3- (metylsulfonyl) fenyl) propansyre

 

 

Populære tags: 1025967-78-5 LiftErast, China 1025967-78-5 LiftEgast Produsenter, leverandører